An Integrated System for Cancer-Related Genes Mining from Biomedical Literatures
نویسندگان
چکیده
According to statistics, the rate of having cancer is relatively high for people in developing and developed countries. So cancer can be called as the enemy of human health. With the destruction of ecological environment and with the change of life style and diet, the rate of having cancer during the life of a general individual is one and a quarter and grows continuously by year. Thus, it is important to study the cause of cancer. However, while bio medical researchers search and retrieve bio medical literature, there is a problem of information overloading. Therefore, to survey thousands and hundreds of biomedical literatures by manual browsing is time wasting and difficult to make sure whether required information can be found. Besides, artificial inattention may lead to incorrect analysis information. The purpose of this study is to develop an integrated system for collecting and mining cancer-related gene. This system uses PubMed search engine of NCBI to search and retrieve bio medical literature and sequence of cancer-related gene. Users can combine cancer name and LOH (loss of heterozygosity), or cancer name and CGH (comparative genomic hybridization) to search, retrieve, collect, classify, and extract the biomedical literatures. This system can extract important information to accelerate the study and save plenty of time for biomedical researchers. Besides, this system can also be used on other diseases.
منابع مشابه
Mining protein-protein interaction information on the internet
In this study, a mining system is proposed for finding protein–protein interaction literatures from the databases on the Internet. In this system, we find out discriminating words for protein–protein interaction by way of statistics and the results from literatures. A threshold is also evaluated to check if a given literature is related to protein–protein interactions. In addition, a keypage-ba...
متن کاملHLungDB: an integrated database of human lung cancer research
The human lung cancer database (HLungDB) is a database with the integration of the lung cancer-related genes, proteins and miRNAs together with the corresponding clinical information. The main purpose of this platform is to establish a network of lung cancer-related molecules and to facilitate the mechanistic study of lung carcinogenesis. The entries describing the relationships between molecul...
متن کاملLiverCancerMarkerRIF: a liver cancer biomarker interactive curation system combining text mining and expert annotations
UNLABELLED Biomarkers are biomolecules in the human body that can indicate disease states and abnormal biological processes. Biomarkers are often used during clinical trials to identify patients with cancers. Although biomedical research related to biomarkers has increased over the years and substantial effort has been expended to obtain results in these studies, the specific results obtained o...
متن کاملAn Effective Soft Clustering Approach to Mining Gene Expressions from Multi-Source Databases
In recent years, many technologies that are used to analyze genes were proposed. Huge amount of biological databases, such as microarray data, biomedical literatures, sequence data and genome structure data et al., have formed useful data warehouses to mine gene-gene relations and predict the gene networks in advance. In the field of bioinformatics, the clustering of gene expressions is a commo...
متن کاملClustering Functional Gene Groups by Biomedical Text Mining
– Modern molecular biology techniques generate large amount of information in short period of time. Often researchers need to partition genes, which were produced as a list of interests from some high throughput assays, into function clusters, and formulate a hypothesis for the bioprocess studied based on common functions of genes in a same group. A number of algorithms have been developed for ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- IJCSA
دوره 3 شماره
صفحات -
تاریخ انتشار 2006